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O.J. Simpson
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Norm Van Brocklin
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Frank Clarke
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Most Yards Rushing
250 - O.J. Simpson, Buffalo vs. New England, Sept. 16, 1973
220 - Michael Turner, Atlanta vs. Detroit, Sept. 7, 2008
216 - Eddie George, Tennessee vs. Oakland, Aug. 31, 1997
206 - George Rogers, New Orleans vs. St. Louis, Sept. 4, 1983
202 - Gerald Riggs, Atlanta vs. New Orleans, Sept. 2, 1984
Most Yards Passing
554 - Norm Van Brocklin, L.A. Rams vs. N.Y. Yanks, Sept. 28, 1951
473 - Dan Marino, Miami vs. New England, Sept. 4, 1994
441 - Kurt Warner, St. Louis vs. Denver, Sept. 4, 2000
421 - Drew Bledsoe, New England vs. Miami, Sept. 4, 1994
415 - Glen Foley, N.Y. Jets vs. San Francisco, Sept. 6, 1998
Most Yards Receiving
241 - Frank Clarke, Dallas vs. Washington, Sept. 16, 1962
217 - Anquan Boldin, Arizona vs Detroit, Sept. 7, 2003
212 - Hugh Taylor, Washington vs. Philadelphia, Sept. 28, 1947
211 - Lance Alworth , San Diego vs. Denver, Sept. 11, 1965
211 - Irving Fryar, Miami vs. New England, Sept. 4, 1994